Segment of glycosylation-deficient HGFalpha-chain
US7807177B2 · kind B2 · utility
0Cited by
0References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 26, 2004 |
| Grant date | Oct 5, 2010 |
| Priority date | — |
| Expiry date | Mar 18, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4753
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a segment of glycosylation-deficient HGF having mutation(s) introduced into an amino acid sequence so as to prevent glycosylation at at least one glycosylation site of a hepatocyte growth factor (HGF), and a method of producing the same. The segment of glycosylation-deficient HGF of the present invention has the same activity as that of a segment of glycosylated HGF, therefore, it is useful as an alternate for a segment of glycosylated HGF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.