Methods and materials for pain management

US7807651B1 · kind B1 · utility

Assignee

• The Board of Regents of the University of Texas System · US

Inventors

• Li-Yen Mae Huang · Galveston, US
• Yanping Gu · Dongguan, CN
• Ya Xu · Zhengzhou, CN

Key dates

• Filing date: Dec 14, 2007
• Grant date: Oct 5, 2010
• Expiry date: Dec 14, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2830/008
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are methods for treating pain in a subject. The method includes upregulating expression of opioid receptors in the subject's dorsal root ganglion neurons. Also disclosed are methods of treating neuropathic and/or chronic pain in a subject. The method includes upregulating expression of μ-opioid receptors in the subject's large dorsal root ganglion neurons.