Diketo-Piperazine and Piperidine derivatives as antiviral agents

US7807676B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Tao Wang · Farmington, US
• John F. Kadow · Wallingford, US
• Zhongxing Zhang · Wallingford, US
• Zhiwei Yin · Glastonbury, US
• Nicholas A. Meanwell · East Hampton, US
• Alicia Regueiro-Ren · Wallingford, US
• Jacob Swidorski · Wallingford, US
• Ying Han · Cheshire, US
• David J. Carini · Wilmington, US
• Lawrence G. Hamann · North Grafton, US

Key dates

• Filing date: Oct 23, 2007
• Grant date: Oct 5, 2010
• Expiry date: Apr 29, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This disclosure provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with diketo piperazine and piperadine derivatives that possess unique antiviral activity. More particularly, the present disclosure relates to compounds useful for the treatment of HIV and AIDS.