Substituted thiophene carboxylic amide glucagon receptor antagonists, preparation and therapeutic uses
US7807702B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Nov 21, 2006 |
| Grant date | Oct 5, 2010 |
| Priority date | — |
| Expiry date | Mar 21, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.