Patent · US Active

RNA detection assays

US7807806B2 · kind B2 · utility

44Cited by

20References

7Claims

0Family size

Assignee

Third Wave Technologies, Inc. · US

Inventors

Hatim Allawi · Madison, US
Brad T. Argue · Sun Prairie, US
Christian Bartholomay · Madison, US
LuAnne Chehak · Janesville, US
Michelle Curtis · Cottage Grove, US
Peggy S. Eis · Fitchburg, US
Jeff G. Hall · Madison, US
Hon Ip · Madison, US
Lin Ji · Sugar Land, US
Michael W. Kaiser · Madison, US
Robert Kwiatkowski · Verona, US
Andrew A. Lukowiak · Stoughton, US
Victor Lyamichev · Madison, US
Natalie E. Lyamicheva · Madison, US
WuPo Ma · Madison, US
Bruce Neri · Madison, US
Sarah Olson · Middleton, US
Marilyn Olson-Munoz · Madison, US
James J. Schaefer · Madison, US
Zbigniev Skrzypczynski · Verona, US
Tsetska Y. Takova · Madison, US
Lisa C. Thompson · Madison, US
Kevin L. Vedvik · Sun Prairie, US

Key dates

Filing date	Oct 30, 2007
Grant date	Oct 5, 2010
Priority date	—
Expiry date	Mar 17, 2028

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/143333
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.