Conductive media for electrophoresis
US7811437B2 · kind B2 · utility
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6References
19Claims
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Key dates
| Filing date | Oct 6, 2006 |
| Grant date | Oct 12, 2010 |
| Priority date | — |
| Expiry date | Aug 12, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44747
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A series of low molarity conductive media based on non-buffering univalent cations, such as sodium chloride-sodium acetate (SCA), sodium boric acid (SB), lithium boric acid, and lithium acetate mitigate the “runaway” positive feedback heating loop produced by conventional media containing biological amine buffers and permit improved DNA electrophoresis under the conditions of low salt concentration. These media serve well in ultra-fast DNA electrophoresis and in high-resolution separations of RNA and DNA fragments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.