Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
US7812038B2 · kind B2 · utility
1Cited by
17References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2005 |
| Grant date | Oct 12, 2010 |
| Priority date | — |
| Expiry date | Jul 13, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which α4β1 is involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.