Methods of identifying pancreatic cancer cells
US7816082B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 3, 2008 |
| Grant date | Oct 19, 2010 |
| Priority date | — |
| Expiry date | Mar 3, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods that identify cells as pancreatic cancer cells based on assessing the expression of combinations of target molecules expressed preferentially on pancreatic cancer cells are disclosed. Combinations were initially discovered by microarray analysis and selected based upon tumor specificity, relative lack of cross-reactivity with normal tissues, and applicability as targets of multispecific ligands. The claimed methods encompass measuring the expression of three or more specific target molecules in combination and correlating positive expression of the combination with an identification of the cell as a pancreatic cancer cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.