Genetic polymorphisms associated with neurodegenerative diseases, methods of detection and uses thereof
US7816083B2 · kind B2 · utility
3Cited by
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32Claims
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Key dates
| Filing date | May 1, 2008 |
| Grant date | Oct 19, 2010 |
| Priority date | — |
| Expiry date | May 30, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is based on the discovery of genetic polymorphisms that are associated with neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.