Method for producing an optically active 2-methyl-alkane-1-ol from the corresponding 2-methylalk-2-en-1-al, comprising carbonyl-selective reduction, enantioselective hydration and lipase-catalyzed, stereoselective acylation in order to enrich the desired

US7816107B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Christoph Jäkel · Schifferstadt, DE
• Gunnar Heydrich · Schifferstadt, DE
• Rainer Stürmer · Bad Dürkheim, DE
• Rocco Paciello · Bad Dürkheim, DE

Key dates

• Filing date: Sep 22, 2005
• Grant date: Oct 19, 2010
• Expiry date: Dec 10, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/07
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for preparing optically active 2-methylalkan-1-ol of the general formula (III) comprising the following steps: