Amine derivatives

US7816365B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Kai Schiemann · Darmstadt, DE
• Guenter Hoelzemann · Seeheim-Jugenheim, DE
• Wilfried Rautenberg · Reinheim, DE

Key dates

• Filing date: Nov 5, 2004
• Grant date: Oct 19, 2010
• Expiry date: Dec 11, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of formula (I),which are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and which can be employed, inter alia, for the treatment of tumours.