Patent · US Active

Predicting hepatotoxicity using cell based assays

US7817840B2 · kind B2 · utility

14Cited by

43References

19Claims

0Family size

Assignee

CYTOKINETICS, INC. · US

Inventors

Larry C. Mattheakis · Cupertino, US
Jay Trautman · Pennington, US
Gregg Solar · San Anselmo, US
Jinhong Fan · Berkeley, US
Eugeni Vaisberg · Foster City, US
Cynthia Adams · Palo Alto, US
Aibing Rao · Burlingame, US

Key dates

Filing date	Mar 13, 2006
Grant date	Oct 19, 2010
Priority date	—
Expiry date	Jul 28, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/20152
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.