Patent · US Active

Compositions and methods of producing hybrid antigen binding molecules and uses thereof

US7820165B2 · kind B2 · utility

14Cited by

27References

4Claims

0Family size

Assignee

MERCK SERONO SA · CH

Inventors

Sean D. McKenna · Duxbury, US
Robert Campbell · Wrentham, US
Xuliang Jiang · Braintree, US
Giampiero De Luca · Veyrier, CH
Meijia Yang · East Lyme, US
Christie Ann Kelton · Hopkinton, US
Stephen John ARKINSTALL · Belmont, US
Chaomei He · Wellesley, US
Rene Lynn Schweickhardt · Medfield, US

Key dates

Filing date	Nov 21, 2006
Grant date	Oct 26, 2010
Priority date	—
Expiry date	Nov 21, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure relates to hybrid antigen binding molecules including at least two polypeptide chains, with at least one polypeptide chain comprises an antigen binding moiety linked to an amino acid sequence of a subunit of a heterodimeric proteinaceous hormone. Also disclosed are methods of making and using such hybrid antigen binding molecules for diagnosis and/or therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.