Ketoreductases and uses thereof
US7820421B2 · kind B2 · utility
32Cited by
20References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2008 |
| Grant date | Oct 26, 2010 |
| Priority date | — |
| Expiry date | Dec 16, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y101/01184
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.