Pyrimidine derivatives for the treatment of abnormal cell growth
US7820648B2 · kind B2 · utility
2Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | Dec 20, 2006 |
| Grant date | Oct 26, 2010 |
| Priority date | — |
| Expiry date | Aug 25, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound of the formula 1or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formulaand R1, R2, R13, A, K, M, L1, L2, X, Y1, Y2, Q, salt thereof, wherein R1, R2, R13, A, K, L1, L2, W, X, Z1, Z2, Y1, Y2, Z1, Z2, M, Q, W, X, m, p and q are as defined herein. Such novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.