Pro-drugs of adenosine receptor agonists
US7820811B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 26, 2007 |
| Grant date | Oct 26, 2010 |
| Priority date | — |
| Expiry date | Oct 5, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method of improving oral drug absorption of adenosine analogues by the use of 2′-methoxy adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further relates to compounds that are pro-drugs of adenosine receptor agonists, and to their use as therapeutic compounds, in particular as analgesic or anti-inflammatory compounds, or as disease modifying antirheumatic drugs (DMARDs), and to methods of preventing, treating or ameliorating pain or inflammation using these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.