High speed combination multi-mode ionization source for mass spectrometers
US7820980B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Aug 1, 2007 |
| Grant date | Oct 26, 2010 |
| Priority date | — |
| Expiry date | Nov 16, 2028 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/165
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
The present invention combines ionization modes produced by, for example, electrospray (ESI), atmospheric pressure chemical ionization (APCI), and thermospray for analysis of molecules. Specifically, this invention relates to the creation of a new source apparatus combining APCI and ESI which will interface with existing mass spectrometers, as well as the creation of new mass spectrometers where the present invention would be the ionization source. Furthermore, the present invention relates to an ionization source for a mass spectrometer which features an ion chamber defining an ion path, an electrospray probe for ionizing a sample using electrospray ionization, a corona discharge needle for ionizing a sample using atmospheric pressure chemical ionization, a power supply for applying an electrical potential to one of said electrospray probe and said corona discharge needle, and a solid state switch for directing the electrical potential from the power supply to one of the electrospray probe and said corona discharge needle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.