Patent · US Active

Compounds and methods for selective inhibition of dipeptidyl peptidase-IV

US7825139B2 · kind B2 · utility

27Cited by
62References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 25, 2006
Grant dateNov 2, 2010
Priority date
Expiry dateMay 23, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F5/025
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds that selectively inhibit dipeptidyl peptidase-IV over closely related dipeptidyl peptidases are those of Formula (I):as well as pharmaceutically acceptable salts thereof, cyclic isomers thereof, prodrugs thereof, and solvates thereof, where all the variables are defined herein. These compounds can be used, alone or in combination with other drugs, for the treatment of diabetes and related diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.