Patent · US Active

Method for the production of oxazoles by condensing aromatic aldehydes with α-ketoximes to N-oxides and then reacting the same with activated acid derivatives

US7825144B2 · kind B2 · utility

0Cited by

2References

8Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Wolfgang Holla · Kelkheim, DE
Rolf-Ludwig HOERLEIN · Frankfurt am Main, DE
Berndt Kulitzscher · Esselbach, DE
Wolfgang Laux · Paris, FR
Thomas Stuedemann · Kelkheim, DE
Christoph Tappertzhofen · Frankfurt, DE
Robert J. H. Scheffer · Ingelheim am Rhein, DE

Key dates

Filing date	Jul 27, 2009
Grant date	Nov 2, 2010
Priority date	—
Expiry date	Jul 27, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention is related to a process for preparing compounds of the formula IV by means of conversion of aromatic aldehydes of the formula I using α-ketoximes of the formula II via N-oxides of the formula III to halomethyloxazoles of the formula IV,wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3, o, n1 and n2 are as defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.