Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
US7825244B2 · kind B2 · utility
1Cited by
13References
12Claims
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Key dates
| Filing date | Jun 6, 2006 |
| Grant date | Nov 2, 2010 |
| Priority date | — |
| Expiry date | Aug 30, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C:wherein R1, R2, R99, and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.