Simulated dose calibrator source standard for positron emission tomography radionuclides
US7825372B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 9, 2009 |
| Grant date | Nov 2, 2010 |
| Priority date | — |
| Expiry date | Jun 13, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21F5/015
- WIPO fieldEnvironmental technology
- WIPO sectorChemistry
Abstract
A method for calibration and a calibrator source standard calibrated by the method are provided. The calibration method includes providing mock syringes, or other simulated dose container. A first of the mock syringes is filled with a short half life positron emitter. A second of the mock syringes is filled with a longer half life radionuclide set in a matrix material such as an epoxy. The activities of the two syringes can be determined, ideally in the same ion chamber, for example, against a radioactive source standard having a half life greater than the first and second radionuclides. This allows a conversion factor to be determined which can be used for a calibrator source standard formed as for the second mock syringe (i.e., with the same type of container containing the longer half life radionuclide set in a matrix material), when the calibrator source standard is used as a proxy for calibrating a calibrator for use in determining the activity of a dose container of the same configuration containing a dose of the short lived radionuclide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.