In situ analysis of tissues
US7829291B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 16, 2006 |
| Grant date | Nov 9, 2010 |
| Priority date | — |
| Expiry date | Jan 12, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5082
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides for the simultaneous assessment of a plurality of tissue regions or microregions, the benefit being homogeneity of the sampling, both in terms of tissue content and timing. Discrete regions of a tissue sample, such as those demarcated by microwells formed within the tissue itself or tissue plugs removed from the tissue in a spatially referenced fashion, can be treated with one or more physical or chemical treatments to liberate target molecules of interest. Subsequent analysis of said target molecules by, e.g., mass spectroscopy, permits identification of a variety of biological parameters, including those associated with disease or therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.