Agonists of bitter taste receptors and uses thereof

US7829299B2 · kind B2 · utility

Assignee

• Deutsches Institut fur Ernahrungsforschung Potsdam-Rehbrucke Stiftung Des Offentlichen Rechts · DE

Inventors

• Bernd Bufe · Ferch, DE
• Wolfgang Meyerhof · Norderstedt, DE
• Christina Kuhn · Michendorf, DE

Key dates

• Filing date: Nov 18, 2005
• Grant date: Nov 9, 2010
• Expiry date: Apr 13, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to agonists of the hTAS2R1, hTAS2R3, hTAS2R7 and hTAS2R40 bitter taste receptors, respectively, and their role in bitter taste transduction. The invention also relates to assays for screening molecules that modulate, e.g. suppress or block hTAS2R1, hTAS2R3, hTAS2R7 or hTAS2R40 bitter taste transduction or bitter taste response.