Method for isolating a self-renewing, multipotent, slow-cycling cell
US7829336B2 · kind B2 · utility
2Cited by
5References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 12, 2004 |
| Grant date | Nov 9, 2010 |
| Priority date | — |
| Expiry date | Oct 5, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1323
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods for isolating infrequently-dividing, slow-cycling cells, a feature which is typical of stem cells in their niche. The methods of the present invention are advantageously used as classical stem cells can be isolated. Further provided are methods for generating clonal populations and inhibiting the differentiation of these cells. In addition markers for distinguishing these cells from progenitor cells are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.