Method for construction of oligonucleotide microarrays
US7829505B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 26, 2006 |
| Grant date | Nov 9, 2010 |
| Priority date | — |
| Expiry date | Jun 26, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00637
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed herein is a method for the preparation of oligonucleotide microarrays obviating the drawbacks to an extent, such as time consuming complex chemical reactions, preparation of modified supports/oligomer modifying reagents, use of activating/condensing reagent, low signal to noise ratio, poor immobilization and hybridization efficiencies, etc. Further, the prepared arrays can be used to detect single or multiple nucleotide mismatches using hybridization assay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.