Patent · US Active

Method and pharmaceutical composition for treating psoriasis, squamous cell carcinoma and/or parakeratosis by inhibiting expression of squamous cell carcinoma-related antigen

US7829547B2 · kind B2 · utility

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Assignee

Inventors

Key dates

Filing dateSep 22, 2005
Grant dateNov 9, 2010
Priority date
Expiry dateJun 4, 2026

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/205
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In a first aspect thereof, the present invention provides a method for treatment and/or prevention of a disease selected from the group consisting of psoriasis and squamous cell carcinoma by inhibiting the expression of squamous cell carcinoma antigen (SCCA) by cells. In another aspect thereof, the present invention provides a method for screening for substances that inhibit epidermal parakeratosis, wherein the activity of a candidate substance that inhibits cysteine protease inhibitory activity possessed by squamous cell carcinoma antigen 1 (SCCA-1) is used as an indicator.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.