Detection of tuberculosis and infection by Mycobacterium tuberculosis using HBHA

US7833699B2 · kind B2 · utility

Assignees

• INSTITUT PASTEUR DE LILLE · FR
• INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) · FR
• UNIVERSITÉ LIBRE DE BRUXELLES · BE
• UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 · FR

Inventors

• Camille Locht · Wannehain, FR
• Francoise Mascart · Brussels, BE
• Stephane Theophile Temmerman · Rixensart, BE
• Jean-Michel Hougardy · Itterbeek, BE
• Sammy Place · Tubize, BE
• Christian Sergheraert · Hazebrouck, FR

Key dates

• Filing date: Dec 28, 2006
• Grant date: Nov 16, 2010
• Expiry date: Oct 13, 2027

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5695
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention concerns methods for in vitro detection of an infection by Mycobacterium tuberculosis in mammals, and methods for in vitro distinction between mammals infected with Mycobacterium tuberculosis in which the disease is declared (active form) and mammals which are infected but asymptomatic for tuberculosis (latent form), and a method for in vitro distinction between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis. The present invention also pertains to kits for detection and distinction between infected mammals presenting tuberculosis symptoms and infected mammals with no disease development, and a kit for distinguishing between mammals presenting an active form of tuberculosis and mammals not infected by M. tuberculosis or presenting a latent form of tuberculosis.