4-amino-5-cyanopyrimidine derivatives
US7834002B2 · kind B2 · utility
1Cited by
33References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2005 |
| Grant date | Nov 16, 2010 |
| Priority date | — |
| Expiry date | Feb 26, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.