Patent · US Active

Phenyl-[1,2,4]-oxadiazol-5-one derivatives, pharmaceutical compositions and therapeutic use thereof

US7834030B2 · kind B2 · utility

0Cited by

2References

32Claims

0Family size

Assignee

Sanofi-Aventis · FR

Inventors

Stefanie Keil · Frankfurt am Main, DE
Patrick Bernardelli · Fontenay-aux-Roses, FR
Matthias Urmann · Eschborn, DE
Hans Matter · Langenselbold, DE
Wolfgang Wendler · Bad Camberg, DE
Maike Glien · Frankfurt am Main, DE
Karen Chandross · Somerville, US
Lan-Ying Lee · Somerville, US

Key dates

Filing date	Mar 26, 2008
Grant date	Nov 16, 2010
Priority date	—
Expiry date	Mar 26, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention comprises phenyl-[1,2,4]-oxadiazol-5-one derivatives of the general formula I:wherein the R1-R10 and B, U, V, W, X, Y and Z substituents are defined herein. The claimed invention also comprises the compounds isomers and their physiologically acceptable salts as well as processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.