Patent · US Active

Recombinant C140 receptor, its agonists and antagonists, and nucleic acids encoding the receptor

US7834143B2 · kind B2 · utility

0Cited by
11References
8Claims
0Family size

Inventors

Key dates

Filing dateJul 11, 2007
Grant dateNov 16, 2010
Priority date—
Expiry dateJul 11, 2027

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2500/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Nucleic acid molecules encoding the C140 cell surface receptor have been cloned and sequenced. The availability of C140 receptor DNA permits the recombinant production of the C140 receptor which can be produced on the surface of a cell, including an oocyte. The nucleic acid molecules are useful in an assay for detecting a substance which affects C140 receptor activity, either receptor agonists or antagonists. Further, the elucidation of the structure of the C140 receptor permits the design of agonist and antagonist compounds which are useful in such assays. The availability of the C140 receptor also permits production of antibodies specifically immunoreactive with one or more antigenic epitopes of the C140 receptor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.