Method and apparatus for monitoring alteration of flow characteristics in a liquid sample
US7837941B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 7, 2006 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Jul 30, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/86
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for measuring blood coagulation time is formed from a first substrate; a second substrate; a spacer layer disposed between the first and second substrates, said spacer layer having an opening formed therein defining a sample receiving chamber, a vented sink chamber, and an elongated reservoir forming a conduit for liquid movement between the sample receiving chamber and the sink chamber; a first electrode disposed on the first substrate, said first electrode being exposed in the reservoir portion through a first opening in the spacer layer; and a second electrode disposed on the second substrate, said second electrode being exposed in the reservoir portion through a second opening in the spacer layer. The device of the invention is used in combination with an apparatus that is connected to the first and second electrodes for measuring current flow between the first and second electrodes. Changes in observed current are indicative of flow through the device, and a cessation of flow indicates coagulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.