Patent · US Active

In vivo expanded NKT cells and methods of use thereof

US7837990B2 · kind B2 · utility

0Cited by

1References

18Claims

0Family size

Assignees

The Rockefeller University · US
KYOWA HAKKO KIRIN CO., LTD. · JP

Inventors

Madhav Dhodapkar · New York, US
Ralph M. Steinman · Westport, US

Key dates

Filing date	Mar 20, 2006
Grant date	Nov 23, 2010
Priority date	—
Expiry date	Jul 6, 2027

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2502/11
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to the in vivo expansion of NKT cells by their exposure to mature dendritic cells expressing α-galactosyl ceramide and to methods of use thereof in modulating immune responses, such as anti-cancer responses, and enhancing memory responses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.