Antibody specific for mutant presenilin 2 and method of use thereof
US7838247B2 · kind B2 · utility
0Cited by
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5Claims
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Key dates
| Filing date | Aug 20, 2007 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Sep 21, 2027 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/809
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes the identification, isolation, cloning, and determination of the Alzheimer Related Membrane Protein (ARMP) gene on chromosome 14 and a related gene, E5-1, on chromosome 1. Normal and mutant copies of both genes are presented. Transcripts and products of these genes are useful in detecting and diagnosing Alzheimer's disease, developing therapeutics for treatment of Alzheimer's disease, as well as the isolation and manufacture of the protein and the construction of transgenic animals expressing the mutant genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.