Entrapped stem cells and uses thereof
US7838291B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 10, 2007 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Jun 6, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the stem cells, embryonic stem cells in particular. It has been found that, when these stem cells are entrapped such that their proliferation is inhibited, they produce material which inhibits the proliferation of other, non-entrapped cells, including stem cells and neoplastic and/or hyperproliferative, but otherwise normal cells. It has also been found that entrapped cancer cells will produce material which inhibits the proliferation of stem cells. Further, it has been found that the entrapment of the stem cells inhibits their differentiation and thus the entrapment process can serve as a long-term storage device for maintaining the undifferentiated state of at least a portion of the entrapped cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.