Template-fixed peptidomimetics as medicaments against HIV and cancer
US7838496B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | May 2, 2003 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Jan 26, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Template-fixed β-hairpin peptidomimetics of the General Formula (I); wherein Z1 and Z2 are template-fixed chains of 4 and 6 or 5 and 7 α-amino acid residues and salts thereof. They have CXCR4-antagonizing properties and can be used as medicaments. These β-sheet peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.