Embolization using degradable crosslinked hydrogels
US7838699B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 14, 2003 |
| Grant date | Nov 23, 2010 |
| Priority date | — |
| Expiry date | Aug 25, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
One aspect of the present invention relates to a method of temporarily embolizing a blood vessel using a hydrolytically degradable crosslinked hydrogel as an embolus. In certain embodiments, the hydrolytically degradable crosslinked hydrogel substantially hydrolyzes only at about physiological pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel is stable at low pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel comprises a marker molecule, such as a dye, radiopaque, or an MRI-visible compound. It is to be understood that both the foregoing general description and the following detailed description are exemplary, and are intended to provide further explanation of the invention as claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.