Patent · US Active

Use of CXCL6 chemokine for inducing precursor cells into chondrocytes

US7842502B2 · kind B2 · utility

0Cited by

5References

2Claims

0Family size

Assignee

TIGENIX NV · BE

Inventors

Frank Luyten · Rockville, US
Cosimo De Bari · Leuven, BE
Francesco Dell'Accio · London, GB

Key dates

Filing date	Dec 29, 2008
Grant date	Nov 30, 2010
Priority date	—
Expiry date	Dec 29, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention disclosed the expression of CXCL6 by cells which are able to form stable cartilage. The invention describes the use of these cells and of CXCL6 to promote cartilage (and underlying bone) formation e.g. in the repair of cartilage or osteochondral defects. The invention further describes the use of chemokines in the modulation of progenitor cell differentiation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.