Hybrid recombinases for genome manipulation
US7842503B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Apr 29, 2005 |
| Grant date | Nov 30, 2010 |
| Priority date | — |
| Expiry date | Jan 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides methods to site-specifically manipulate genomes by using hybrid recombinases. Hybrid recombinases comprise a modified catalytic domain from a unidirectional serine phage integrase, fused to a foreign DNA recognition domain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.