Diphenylazetidinone derivatives possessing cholesterol absorption inhibitor activity

US7842684B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Malin Lemurell · Mölndal, SE
• Ingemar Starke · Gothenburg, SE

Key dates

• Filing date: Apr 25, 2007
• Grant date: Nov 30, 2010
• Expiry date: Apr 25, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides 2-azetidinone derivatives, or pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof, comprising formula (I):wherein the substituents are as herein defined. The compounds possess cholesterol absorption inhibitory activity and are accordingly of value in the treatment of disease states associated with hyperlipidaemic conditions.