Pyridine methylene azolidinones and use thereof phosphoinositide inhibitors
US7842698B2 · kind B2 · utility
8Cited by
0References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 2, 2005 |
| Grant date | Nov 30, 2010 |
| Priority date | — |
| Expiry date | Feb 28, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pyridine methylene azolidinone compounds of Formula (I)for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, allergy, asthma, pancreatitis, multi-organ failure, kidney diseases, platelet aggregation, cancer, sperm motility, graft rejection or lung injuries. Specifically, the present invention is related to pyridine methylene azolidinone derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide-3-kinases, PI3Ks.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.