Patent · US Active

Methods of treating pre-eclampsia and eclampsia

US7846433B2 · kind B2 · utility

5Cited by

23References

33Claims

0Family size

Assignee

Beth Israel Deaconess Medical Center, Inc. · US

Inventors

S. Ananth Karumanchi · Sharon, US
Sharon Maynard · Emmaus, US
Vikas P. Sukhatme · Boston, US

Key dates

Filing date	Feb 12, 2008
Grant date	Dec 7, 2010
Priority date	—
Expiry date	Feb 12, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/368
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are methods for diagnosing pre-eclampsia and eclampsia. Also disclosed herein are methods for treating pre-eclampsia and eclampsia using compounds that increase VEGF or PlGF levels or compounds that decrease sFlt-1 levels. Compounds that inhibit the binding of VEGF or PlGF to sFlt1—are also disclosed herein for the treatment of pre-eclampsia or eclampsia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.