Antibody composition-producing cell in which enzyme expression is inhibited by RNAi
US7846725B2 · kind B2 · utility
19Cited by
59References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 1, 2008 |
| Grant date | Dec 7, 2010 |
| Priority date | — |
| Expiry date | Mar 17, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, wherein the expression of GDP-mannose 4,6-dehydrogenase is inhibited by RNA interference.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.