Metabolically activated recombinant viral vectors and methods for their preparation and use
US7846729B2 · kind B2 · utility
25Cited by
20References
9Claims
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Key dates
| Filing date | Aug 6, 2007 |
| Grant date | Dec 7, 2010 |
| Priority date | — |
| Expiry date | Dec 8, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Recombinant viral vectors, especially parvovirus vectors such as adeno-associated virus (AAV) vectors, capable of enhanced expression of heterologous sequences, and methods for their construction and use, are provided. The vectors have a structure, or are capable of rapidly adopting a structure, which involves intrastrand base pairing of at least one region in a heterologous sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.