Patent · US Active

Compounds and compositions as protein kinase inhbitors

US7846923B2 · kind B2 · utility

2Cited by
0References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 11, 2007
Grant dateDec 7, 2010
Priority date
Expiry dateMay 11, 2027

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, Bcr-Abl(T315I), ALK, BLK, BMX, BRK, C-kit, c-RAF, CSK, c-SRC, EGFR, Fes, FGFR3, Flt3, Fms, Fyn, IGF-1R, IR, JAK(2), JAK(3), KDR, Lck, NLK, p70S6K, PDGFRα, Ros, SAPK2α, SGK, SIK, Syk, Tie2 and TrkB kinases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.