Medicament microdevice delivery system, cartridge and method of use

US7850663B2 · kind B2 · utility

Assignee

• Becton, Dickinson and Company · US

Inventors

• Vincent J. Sullivan · Morrisville, US
• Ronald J. Pettis · Durham, US
• John Mikszta · Durham, US
• John Dekker · Cary, US
• Wendy Woodley · Cary, US
• Anjana Bhuta Wills · Cary, US
• Matthew S. Ferriter · Chapel Hill, US
• C. Robin Hwang · Thousand Oaks, US

Key dates

• Filing date: Jun 1, 2004
• Grant date: Dec 14, 2010
• Expiry date: May 18, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2205/075
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method and device for intradermal delivery of a reconstituted powdered medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the powdered medicament may be located within said chamber. At least one burstable membrane retains a powdered medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the powdered medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin.