Manipulation of cytokine levels using CD83 gene products
US7850968B2 · kind B2 · utility
0Cited by
4References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 2, 2009 |
| Grant date | Dec 14, 2010 |
| Priority date | — |
| Expiry date | Oct 2, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for modulating cytokine levels, GM-CSF levels and the immune system using CD83 nucleic acids, CD83 polypeptides, anti-CD83 antibodies and factors that influence CD83 activity or expression. The invention also provides mice having a mutant CD83 gene and mice having a transgenic CD83 gene, which are useful for defining the role of CD83 in the immune system and for identifying compounds that can modulate CD83 and the immune system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.