Patent · US Active

Functionalized apertures for the detection of chemical and biological materials

US7851203B2 · kind B2 · utility

17Cited by

2References

14Claims

0Family size

Assignee

Lawrence Livermore National Security, LLC · US

Inventors

Sonia Letant · Benicia, US
Anthony W. Van Buuren · Livermore, US
Louis Terminello · Pleasanton, US
Michael P. Thelen · Danville, US
Louisa Hope-Weeks · Brentwood, US
Bradley R. Hart · Brentwood, US

Key dates

Filing date	Oct 1, 2003
Grant date	Dec 14, 2010
Priority date	—
Expiry date	Feb 14, 2027

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01D2323/30
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

Disclosed are nanometer to micron scale functionalized apertures constructed on a substrate made of glass, carbon, semiconductors or polymeric materials that allow for the real time detection of biological materials or chemical moieties. Many apertures can exist on one substrate allowing for the simultaneous detection of numerous chemical and biological molecules. One embodiment features a macrocyclic ring attached to cross-linkers, wherein the macrocyclic ring has a biological or chemical probe extending through the aperture. Another embodiment achieves functionalization by attaching chemical or biological anchors directly to the walls of the apertures via cross-linkers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.