Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
US7851437B2 · kind B2 · utility
102Cited by
64References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2009 |
| Grant date | Dec 14, 2010 |
| Priority date | — |
| Expiry date | Nov 18, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.