Patent · US Active

Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides

US7851596B2 · kind B2 · utility

10Cited by

15References

2Claims

0Family size

Assignee

HUMAN GENOME SCIENCES, INC. · US

Inventors

Reiner Gentz · Silver Spring, US
Brent L. Kreider · Bedford, US
Jun Zhang · Xiamen, CN
Michael Antonaccio · Princeton, US
Donna Mendrick · Mount Airy, US
Pablo Jimenez · Ellicott City, US
Vikram Patel · Germantown, US
Craig Rosen · Laytonsville, US
Mark D. Adams · Potomac, US
Haodong Li · Gaithersburg, US
Steven Ruben · Olney, US

Key dates

Filing date	Apr 28, 2008
Grant date	Dec 14, 2010
Priority date	—
Expiry date	Apr 28, 2028

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3 and chemokine β8 (CKβ8 or ckb-8)); a human monocyte-colony inhibitory factor (M-CIF) polypeptide (previously termed MIP1-γ and chemokine β1 (CKβ1 or ckb-1)), and a macrophage inhibitory protein-4 (MIP-4), as well as MPIF-1, M-CIF and/or MIP-4 polypeptides themselves, as are vectors, host cells and recombinant methods for producing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.