Methods of controlling proliferation and differentiation of stem and progenitor cells
US7855075B2 · kind B2 · utility
1Cited by
185References
17Claims
0Family size
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Key dates
| Filing date | May 19, 2008 |
| Grant date | Dec 21, 2010 |
| Priority date | — |
| Expiry date | May 19, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for permitting the stem cells to proliferate and, at the same time, for reducing a capacity of the stem cells to differentiate
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.